Liver transplant is a surgical procedure which is performed to remove a diseased liver that has been damaged to such an extent that it can no longer function properly. It is a procedure for replacing damaged liver with a healthy liver from a donor. It's an extremely complicated surgery that requires an experienced and knowledgeable surgeon with strict pre-operative preparedness and detailed medical history of the patient as well as the donor.
Liver transplantation Surgery is generally carried out in two ways depending upon the source of liver donation,
- Liver transplant from Living Donor.
- Liver transplant from deceased donor, also known as Cadaveric Liver transplant.
Although, most liver transplant operations use livers from deceased donors, however a liver may also come from a living donor. In case of a living donor, it is essential to get an approval from the ethical committee.
Who Requires a Liver Transplant?
A liver transplant is needed when the liver fails to perform 85- 90% of the function. A liver failure can be either sudden (acute liver failure) or can occur slowly over months and years (chronic liver failure) and happens because of viral hepatitis, drug-induced injury, Wilson's disease, Alcoholism, Early-stage liver cancer, Hemochromatosis, Primary biliary cholangitis, infection etc. Children with bile and digestive issues are more prone to liver failure.
The common symptoms that a person with the damaged liver experiences are Nausea, Loss of appetite, Fatigue and Diarrhoea. However, when the Liver failure becomes severe, the symptoms become more serious including Jaundice, Bleeding easily, Swollen abdomen, Mental disorientation, or confusion (known as hepatic encephalopathy), Sleepiness and even Coma.
However, there could be a possibility that a liver transplant patient may get a suitable match for surgery but he/she may not be considered fit for a transplant. This generally happens when a person is affected by certain condition/ diseases that affects the chances of the success rate. Some of such conditions are acute malnutrition, infection, long-lasting obstructive pulmonary disease, heart failure, AIDS, mental condition, continuous alcohol, or drugs intake etc. Before going for a liver transplant, check out and confirm with your surgeon that whether you are eligible or not for transplant.
The pre-operative procedure can go for weeks depending upon the medical condition of the patient, MELD score, availability and fitness of the liver, a mandatory No-Obligation Certificate etc.
Liver Transplant- Successful or Unsuccessful
Liver Transplant is successful treatment and generally, the overall patient survival for the entire surgery ranges between was 60-70%. The long-term success rate of liver transplant surgery is high and one can expect a survival rate of 60%- 70% after 15-20 years of surgery. The success of liver transplant depends on a perfect match with a donor, on the body size and blood type of patient, MELD score etc. The success rate is better amongst children, female, sportspersons etc. who are generally able to resume their activities and can live a normal life after 3-6 months of the surgery. Though, there is 4-6% risk, usually related with the technically complicated procedures.
Patients can undergo some problems depending upon the time after the transplant. In the initial 1-2 years, the most common problems faced by people are biliary stricture, infections and rejection of the liver by the body. But at Fortis Escorts, we offer lowest biliary complication rate of just 5-6%. Our new procedure and the innovative technologies invented by the professional team is what helps us to deliver the best.
Fortis Escorts & Liver Transplant
At Fortis Escorts, we have set up a benchmark in performing the successful Liver Transplants surgeries with the success rate is 90-95%. The surgeries are performed by the team of the country's most experienced, reputed, and patient friendly experts who have excellent records in terms of patient care and outcomes. Our Liver & Digestive Diseases Institute provides comprehensive high-end care for a wide spectrum of liver disorders through a highly qualified, experienced team of specialists supported by state-of-the-art technology. The institute prides itself in providing compassionate care in a soothing ambience with a high premium on patient satisfaction. We are known for providing safe, high quality care to our patients. Our surgeons are admired for providing their patients with utmost care which also helps in lowering expenses for dealing with biliary complications. Our team brings together the best brains in the country who have worked at various centres across the globe under one unit with a rich cumulative experience of working at various successful Transplant centres in India, as the outcome matters while choosing a hospital for your Liver Transplant. We at Fortis Escorts, ensure 100% donor safety by adhering to standardized safety protocols.
Risks and Side Effects
Liver transplant is a complicated surgery which may lead to several complications post-surgery. However, it is not that every patient experience these problems, there are only few cases which may occur. Most of complications can be prevented if the patients firmly follow the instructions given by their doctor and regularly visit for check-ups. Liver transplant surgery carries a risk of significant complications which includes:
- Bile duct complications, including bile duct leaks or shrinking of the bile ducts
- Bleeding: It may occur during or post liver transplant due to changes in the blood clotting parameters
- Blood clots
- Failure of donated liver
- Infection: The immunity of the body decreases due to the continuous intake of immuno suppressive medicines which may lead to a higher chance of getting bacterial, fungal and viral infections.
- Memory and thinking problems
- Rejection of donated liver
Side effects of anti-rejection medications
After a liver transplant, you'll take medications for the rest of your life to help prevent your body from rejecting and attacking the donated liver. These medications can cause a variety of side effects, including:
- Bone thinning
- High blood pressure
- High cholesterol
Tests, Procedures and Consultations
- Diagnostic Endoscopy
- Therapeutic UGI Endoscopy
- Capsule Endoscopy
- Therapeutic colonoscopy
- Endoscopic ultrasonography
- Other Laboratory tests, including blood and urine tests to assess the health of your organs, including your liver
- Imaging tests, such as an ultrasound of your liver
- Heart tests to determine the health of your cardiovascular system
- A general health exam, including routine cancer screening tests, to evaluate your overall health
- Nutrition counselling with dietitians who assess your nutritional status and make recommendations regarding nutritional intake before and after transplant
- Psychological evaluation to determine whether you fully understand the risks of a liver transplant
- Meetings with social workers who assess your support network to determine whether you have friends or family to help care for you after transplant
- Addiction counselling to help people with alcohol, drug or tobacco addictions to quit
- Financial counselling to help you understand the cost of a transplant and post-transplant care and to determine what costs are covered by insurance
Dr. Vivek Vij:
A pioneering liver transplant surgeon credited with developing living donor surgery and standardizing safety protocols to achieve a 100% donor safety profile since the time of its inception in the country. Dr. Vij and his team have a cumulative experience of performing more than 2500 liver transplants, having performed majority of them at Fortis Hospital, Noida with a record 95% patient and 100% donor success rate. He is the recipient of many awards and recognitions including Roche Preceptorship, University of Alabama, Birmingham, USA, International Liver Transplant Society (ILTS), Chicago among many others.
His expertise has helped patients not only from the Indian subcontinent but also patients coming from Iraq, Oman, Uzbekistan, Mongolia, Yemen etc. His dedication and compassion along with the hard work from his team has helped Fortis to become a renowned and trusted name for the treatment of liver diseases not just in India but complete south-east Asia.
Dr. Manav Wadhawan:
Dr. Manav Wadhawan is a Senior Consultant, Gastroenterology in Liver & Digestive Institute, Fortis Escorts. He has been associated with National Organizations like AIIMS, GB Pant Hospital, Sir Ganga Ram Hospital and Indraprastha Apollo Hospital. Dr Manav Wadhawan has received several awards, notable being: Young Investigator Award by International Liver Transplant Society (ILTS) in 2013, Plenary Oral presentation award by Indian Society of Gastroenterology in 2012, Plenary Oral presentation award by Asia Pacific Society for Study of Liver (APASL) in 2011 & 2004, Plenary Oral presentation award by International Association of Study of Liver (IASL) in 2004. He has been invited for over 200 lectures at various national & international society meetings.
Dr. Vivek Vij
Liver Transplant Causes
Dr. Vivek Vij
Need for Liver Transplant
Dr. Vivek Vij
What is Liver Transplant
Dr. Vivek Vij
When do we need Liver Transplant?
Dr. Vivek Vij
Life after Liver Transplant
Dr. Vivek Vij